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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6
All Species:
15.45
Human Site:
T899
Identified Species:
28.33
UniProt:
Q03468
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03468
NP_000115.1
1493
168416
T899
A
S
R
Q
P
L
I
T
R
Y
N
E
D
T
S
Chimpanzee
Pan troglodytes
XP_507781
1491
168031
T897
A
S
R
Q
P
L
I
T
R
Y
N
E
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001107536
1496
168876
T902
A
S
R
Q
P
L
I
T
R
Y
N
E
D
T
S
Dog
Lupus familis
XP_534944
1486
168108
T894
A
S
R
Q
P
L
I
T
R
Y
N
E
D
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001100766
1325
148468
S766
G
Q
R
V
L
L
F
S
Q
S
R
Q
M
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508174
968
109820
R409
C
R
L
T
A
E
Q
R
E
V
Y
Q
N
F
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24368
1027
118855
C467
L
D
I
L
E
D
Y
C
H
W
R
N
Y
N
Y
Honey Bee
Apis mellifera
XP_001120586
932
107557
Q373
S
L
P
E
K
N
E
Q
V
L
F
C
S
L
T
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
Q450
L
L
M
K
F
K
E
Q
G
S
R
V
L
I
F
Sea Urchin
Strong. purpuratus
XP_001193315
953
107227
S394
P
L
I
T
K
F
N
S
D
P
R
I
F
L
F
Poplar Tree
Populus trichocarpa
XP_002307656
1206
134941
R646
Y
R
C
A
V
V
L
R
D
L
I
M
P
Y
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWY3
1057
122611
L498
K
M
V
L
L
D
K
L
L
P
K
L
K
E
R
Baker's Yeast
Sacchar. cerevisiae
P40352
1085
124509
F526
K
L
G
T
L
P
V
F
Q
Q
Q
F
V
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.3
N.A.
N.A.
70.1
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
20
31.4
20.6
36.4
Protein Similarity:
100
99.4
97.9
89.1
N.A.
N.A.
76.4
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
35.7
43.8
35.7
45.8
P-Site Identity:
100
100
100
100
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
N.A.
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
20
6.6
6.6
Percent
Protein Identity:
29.4
N.A.
N.A.
23.5
28.4
N.A.
Protein Similarity:
44.9
N.A.
N.A.
38.2
43.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
16
0
0
16
0
0
0
31
0
0
% D
% Glu:
0
0
0
8
8
8
16
0
8
0
0
31
0
8
0
% E
% Phe:
0
0
0
0
8
8
8
8
0
0
8
8
8
8
16
% F
% Gly:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
16
0
0
0
31
0
0
0
8
8
0
16
8
% I
% Lys:
16
0
0
8
16
8
8
0
0
0
8
0
8
0
0
% K
% Leu:
16
31
8
16
24
39
8
8
8
16
0
8
8
24
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
31
8
8
8
0
% N
% Pro:
8
0
8
0
31
8
0
0
0
16
0
0
8
0
8
% P
% Gln:
0
8
0
31
0
0
8
16
16
8
8
16
0
0
0
% Q
% Arg:
0
16
39
0
0
0
0
16
31
0
31
0
0
0
8
% R
% Ser:
8
31
0
0
0
0
0
16
0
16
0
0
8
0
31
% S
% Thr:
0
0
0
24
0
0
0
31
0
0
0
0
0
31
8
% T
% Val:
0
0
8
8
8
8
8
0
8
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
31
8
0
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _